Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation
نویسندگان
چکیده
منابع مشابه
Holocaust or Benevolent Paternalism? Intergenerational Comparisons on Collective Memories and Emotions about Belgium’s Colonial Past
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Developmental exposure to bisphenol A alters expression and DNA methylation of Fkbp5, an important regulator of the stress response
Bisphenol A (BPA), an abundant endocrine disruptor, affects stress-responsiveness and related behaviors in children. In rats, perinatal BPA exposure modifies stress response in pubertal offspring via unknown mechanisms. Here we examined possible epigenetic modifications in the glucocorticoid receptor gene and its regulator Fkbp5 in hypothalamus and hippocampus of exposed offspring. We found inc...
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To what extent are children’s opportunities for upward economic mobility shaped by the neighborhoods in which they grow up? We study this question using data from de-identified tax records on more than five million children whose families moved across counties between 1996 and 2012. The study consists of two parts. In part one, we show that the area in which a child grows up has significant cau...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2016
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2015.08.005